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phenobarbital will lessen the extent or outcome of flurbiprofen by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unidentified.phenobarbital will minimize the extent or effect of diclofenac by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Not known.phenobarbital will lessen the level or impact of amlodipine b